A person’s work experience is an obvious indication of what they can do in a job, but it may also reflect the kind of person they are (though that can be taken too far).
Clearly, someone who wants to be a consultant surgeon needs to build up relevant experience through the various steps of training, specialisation and working with patients. Without it, they will fail. For career changers, the position is less clearcut. Yet work experience needs careful exploration for evidence of both skills and of character.
In either event, prepare work experience stories as part of your job search. These need to set out a problem you faced, what you did to address it, and the result achieved. Not only will this bring out the value of your experience, but it will also feed into your CV and give you ammunition for the interview.